Phenanthroindolizidine alkaloids from Vincetoxicum pumilum
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منابع مشابه
Anti-inflammatory mechanisms of phenanthroindolizidine alkaloids.
The molecular mechanisms for the anti-inflammatory activity of phenanthroindolizidine alkaloids were examined in an in vitro system mimicking acute inflammation by studying the suppression of lipopolysaccharide (LPS)/interferon-gamma (IFNgamma)-induced nitric oxide production in RAW264.7 cells. Two of the phenanthroindolizidine alkaloids, NSTP0G01 (tylophorine) and NSTP0G07 (ficuseptine-A), exh...
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Two known phenanthroindolizidine alkaloids, (-)-(R)-13aalpha-antofine (1) and (-)-(R)-13aalpha-6-O-desmethylantofine (2), and two new natural products, (-)-(R)-13aalpha-secoantofine (3) and (-)-(R)-13aalpha-6-O-desmethylsecoantofine (4), were isolated from Cynanchum vincetoxicum. The structures of all compounds were established by means of NMR methods including COSY, NOESY, HSQC, and HMBC exper...
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Asclepiadaceous plants, we have described that the pyrrolizidine alkaloids in Parsonsia laevigata ALSTON and phenanthroindolizidine alkaloids in Tylophora tanakae MAXIM. act as an oviposition-activating substance for Danaid butterflies, Idea leuconoe and Ideopsis similis, respectively. Since Parantica sita lays eggs on the leaves of Marsdenia tomentosa MORREN et DECAISNE and cyclitols such as c...
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An investigation of alkaloids present in the leaves and stems of Tylophora ovata led to the isolation of two new septicine alkaloids and one new phenanthroindolizidine alkaloid, tylophovatines A, B, C (1, 2, and 5), respectively, together with two known septicine and six known phenanthroindolizidine alkaloids. The structures of the new alkaloids 1, 2, and 5 were established by means of spectros...
متن کاملNovel Steroidal Glycosides from the Bulbs of Lilium pumilum.
Examination of the bulbs of Lilium pumilum (Liliaceae) led to the isolation of four novel steroidal glycosides (1-4) with a 2,3,4-trisubstituted β-d-glucopyranosyl unit. In 1 and 3, the α-L-arabinopyranosyl moiety is linked to C-3 of the inner trisubstituted β-D-glucopyranosyl group and is present as an usual ⁴C₁ conformation. In contrast, in 2 and 4, the α-L-arabinopyranosyl moiety, which is a...
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ژورنال
عنوان ژورنال: Biochemical Systematics and Ecology
سال: 2005
ISSN: 0305-1978
DOI: 10.1016/j.bse.2005.01.004